| Until now, research from the National Eye Institute | | | | years or older. This is a very important fact. |
| and others has shown benefit to taking macular | | | | Because aging changes of the retina most |
| degeneration supplements only after you've | | | | commonly develops after age 60, this study |
| developed dry macular degeneration. But a study | | | | informs us that ingesting omega-3 fatty acids at |
| in the June 2008 issue of the professional journal, | | | | least 10 years before that has an important |
| Archives of Ophthalmology has finally shown the | | | | benefit in the prevention of a potentially blinding |
| benefit to previously healthy people in the | | | | eye disease. |
| prevention of both mild and severe forms of this | | | | How does this study compare with AREDS |
| eye disease. Researchers from Australia and | | | | (Age-Related Eye Disease Study)? |
| Singapore published a study entitled, "Dietary | | | | The Age-Related Eye Disease Study was |
| Omega-3 Fatty Acid and Fish Intake in the | | | | completed by the National Eye Institute, part of |
| Primary Prevention of Age-Related Macular | | | | the United States National Institutes of Health in |
| Degeneration: A Systematic Review and | | | | 2001. There are two important ways in which this |
| Meta-analysis." This meta-analysis consisted of a | | | | study differs from AREDS. 1. AREDS looked at |
| mathematical evaluation of the results from nine | | | | the benefit to taking nutritional supplements on |
| previous studies of nearly 89,000 people, of which | | | | the progression of macular degeneration in people |
| more than 3000 developed macular degeneration. | | | | that already had the disease. In contrast, the |
| The authors found that high dietary intake of | | | | omega-3 study evaluated people before they had |
| Omega-3 fatty acids was associates with a 38% | | | | the disease in an effort to determine whether |
| reduction in the risk of late macular degeneration. | | | | AMD could be prevented. 2. AREDS was a |
| Furthermore, people who ate fish twice weekly | | | | randomized, prospective double-blind study |
| not only reduced their risk of late AMD, but also | | | | (neither the participant nor scientists knew |
| early AMD (soft drusen or retinal pigmentary | | | | whether the the person was receiving real |
| changes). | | | | supplement or placebo). The current study of |
| How do Omega-3 Fatty Acids Help Prevent | | | | omega-3 essential fatty acids was a meta-analytic |
| Macular Degeneration? | | | | mathematical evaluation of prior research that had |
| Omega-3 Fatty acids are called "essential" fatty | | | | already been completed. A prospective study is |
| acids, because humans don't have the ability to | | | | widely considered by the scientific community to |
| synthesize them in their bodies. Therefore, they | | | | be the standard of excellence in research. |
| must get these molecules from diet or nutritional | | | | Nevertheless, this study was based upon nine |
| supplements. Omega-3 fatty acids include | | | | studies that by themselves which were |
| alpha-linolenic acid (ALA), docosahexaenoic acid | | | | considered to be of excellent design. Because of |
| (DHA) and eicosapentaenoic acid (EPA). Both DHA | | | | the apparent benefits of Omega-3 fatty acids in |
| and EPA are long-chain omega-3 fatty acids, that | | | | this and previous studies, the National Eye |
| protect against oxidative, inflammatory and | | | | Institute is currently performing the Age Related |
| age-related degenerative changes. These three | | | | Eye Disease Study 2, which is looking not only at |
| damaging processes result in the development of | | | | the benefit of fish oil, but also at the potential |
| age-related macular degeneration. Furthermore, | | | | benefit of the carotenoids, Lutein and Zeaxanthin. |
| long-chain omega-3 FA's, and especially DHA, form | | | | Reference: Dietary É-3 Fatty Acid and Fish |
| a critical part of the healthy retina. | | | | Intake in the Primary Prevention of Age-Related |
| Who Should Take Omega-3 Fatty Acids based on | | | | Macular Degeneration: A Systematic Review and |
| the current study? | | | | Meta-analysis. Chong E, Kreis A, Wong T, Simpson |
| The current study found benefit in the prevention | | | | J, Guymer R. Archives of Ophthalmology, |
| of macular degeneration in people that were 49 | | | | 126(6):826-833. June 2008. |