Some Thoughts on the Cerebrospinal Fluid

Raised intra-cranial pressure due to communicatingpresent in the ventricles.
or non-communicating hydrocephalus is one theThe usual pressure in the recumbent state is 10
common neurological entity in the pediatric groupto 15 cms of CSF and there are less than 3 to 4
of patients. It usually presents with symptoms likewhite cells per mm cube present in the CSF in
projectile vomiting, severe headache, loss of ornormal state. The protein content is 0.15 to 0.45
altered consciousness. Parents are often curiousgram per liter and the glucose content is 2.8 to
to know more about the fluid that gets4.2 mmol per liter. The CSF glucose content is
accumulated leading to hydrocephalus. This articleapproximately 65 per cent of the blood plasma
will discuss few things about cerebrospinal fluid orlevel in the fasting state.  10 - 12% of the total
CSF as is commonly referred to as.protein is of IgG typte and chloride content
The CSF is produced by a structure called asaccounts for up to 120 to 130 mmol per liter.
choroid plexus which is located in the ventriclesThe CSF is ually clear and colorless, but will appear
[these are the cavities in the brain]. The rate ofturbid if it contains more than four hundred white
production is almost 0.3 to 0.4 ml per minute. Theblood cells or two hundred red blood cells per
fluid circulates from the lateral ventricles into thecubic mm. Yellow discoloration, which is also
third ventricle, passing through the foramen ofknown as xanthochromia, is due to the
Munro or the interventricular foramen. From therebreakdown products of red blood cells - which is
it is carried to the forth ventricle through theusually found in case of bleeding into the CSF.
cerebral aqueduct of Sylvius. The CSF thenThe cerebro-spinal fluid can be obtained by lumbar
passes from the fourth ventricle into thepuncture. If it is not possible to do a lumbar
subarachnoid spce vial foramen of Luschka, whichpuncture due to local sepsis or due to a failure
are two laterally placed foramen. There is yetbecause of technical difficulties, a cisternal
another route called as foramen of Magendie atpuncture can be done to obtain CSF.
the roof of the fourth ventricle. It is absorbed byThis is all about normal features of the CSF. Will
the arachnoid villi of the dural sinuses. Everydaydiscuss about the common abnormalities found in
almost half a liter of CSF is produced by thethe CSF examination in another article.
body, but at a time almost 140 ml of CSF is