| GBI Research's report, "The Future of | | | | 4.3.5 Annual Cost of Therapy 58 |
| Ophthalmology Therapeutics, Analysis and Market | | | | 4.3.6 Treatment Usage Patterns 59 |
| Forecasts to 2016 – Strategies to Counter | | | | 4.3.7 Geographical Segmentation 65 |
| Generic Erosion in Key Markets", provides in-depth | | | | 4.3.8 Drivers of Macular Degeneration Market 67 |
| analysis of the unmet needs, drivers and barriers | | | | 4.3.9 Restraints for Macular Degeneration Market |
| that impact the global ophthalmology therapeutics | | | | 67 |
| market. The report analyzes the ophthalmology | | | | 4.4 Allergic Conjunctivitis Market 68 |
| markets in the US, the top five countries in | | | | 4.4.1 Introduction 68 |
| Europe (the UK, Germany, France, Italy and | | | | 4.4.2 Unmet Needs 68 |
| Spain) and Japan. Treatment usage patterns, | | | | 4.4.3 Sales Value 69 |
| sales, prices and volume are forecast until 2016 | | | | 4.4.4 Sales Volume 70 |
| for the key geographies as well as the leading | | | | 4.4.5 Annual Cost of Therapy 71 |
| therapeutic segments. Further, the report | | | | 4.4.6 Treatment Usage Patterns 72 |
| provides competitive benchmarking for the leading | | | | 4.4.7 Geographical Segmentation 78 |
| companies and analyzes the mergers, acquisitions | | | | 4.4.8 Drivers of Allergic Conjunctivitis Market 80 |
| and licensing agreements that shape the global | | | | 4.4.9 Restraints for Allergic Conjunctivitis Market |
| markets. | | | | 80 |
| This report is built using data and information | | | | 5 Global Ophthalmology Therapeutics Market: |
| sourced from proprietary databases, primary and | | | | Geographical Landscape 81 |
| secondary research and in-house analysis by GBI | | | | 5.1 Geographical Break-up 81 |
| Research's team of industry experts. | | | | 5.2 The US 82 |
| Scope | | | | 5.2.1 Sales Value 82 |
| The scope of this report includes: | | | | 5.2.2 Annual Cost of Therapy 83 |
| - Annualized market data for the ophthalmology | | | | 5.2.3 Treatment Usage Patterns 84 |
| market from 2001 to 2009, forecast forward to | | | | 5.3 Top Five Countries in Europe 90 |
| 2016. | | | | 5.3.1 Sales Value 90 |
| - Analysis of the leading therapeutic segments, | | | | 5.3.2 Annual Cost of Therapy 91 |
| including glaucoma, macular degeneration, macular | | | | 5.3.3 Treatment Usage Patterns 92 |
| edema and allergic conjunctivitis. | | | | 5.4 Japan 96 |
| - Analysis of the ophthalmology market in the | | | | 5.4.1 Sales Value 96 |
| leading geographies of the world, which include the | | | | 5.4.2 Annual Cost of Therapy 97 |
| US (United States), the UK (United Kingdom), | | | | 5.4.3 Treatment Usage Patterns 98 |
| Germany, France, Italy, Spain and Japan. | | | | 6 Global Ophthalmology Therapeutics Market: |
| - Market characterization of the ophthalmology | | | | Pipeline Analysis 104 |
| market including market size, the annual cost of | | | | 6.1 Introduction 104 |
| therapy, sales volume and treatment usage | | | | 6.2 Research and Development Pipeline by Phase |
| patterns. | | | | 104 |
| - Key drivers and barriers that have a significant | | | | 6.2.1 Research and Development Pipeline – |
| impact on the market. | | | | Macular Degeneration 105 |
| - Coverage of pipeline molecules in the various | | | | 6.2.2 Research and Development Pipeline – |
| phases of drug development. | | | | Glaucoma 106 |
| - Competitive benchmarking of leading companies | | | | 6.2.3 Research and Development Pipeline – |
| such as Pfizer, Allergan, Inc., Alcon, Inc., Novartis | | | | Macular Edema 106 |
| AG, Merck & Co Inc and Roche. | | | | 6.2.4 Research and Development Pipeline – |
| - Key M&A activities that have taken place in | | | | Allergic Conjunctivitis 107 |
| 2009 and the licensing agreements in the | | | | 6.3 R&D Trends 107 |
| 2008-2009 global ophthalmology market. | | | | 6.3.1 New Promising Treatments for Diabetic |
| Reasons to buy | | | | Retinopathy 107 |
| The report will enhance your decision making | | | | 6.3.2 Combination Drugs Will be a Key Component |
| capability. It will allow you to: | | | | of Ophthalmology Research and Development 107 |
| - Align your product portfolio to the markets with | | | | 6.4 Profiles of Key Drugs in the Glaucoma Pipeline |
| high growth potential. | | | | 108 |
| - Develop market-entry and market expansion | | | | 6.4.1 Saflutan (tafluprost) 108 |
| strategies by identifying the leading therapeutic | | | | 6.4.2 NCX-116 (Formerly PF-03187207) 108 |
| segments and geographic markets poised for | | | | 6.4.3 Catioprost 109 |
| strong growth. | | | | 6.5 Profiles of Key Drugs in Macular Edema and |
| - Reinforce R&D pipelines by identifying new | | | | Diabetic Retinopathy Pipeline 110 |
| target mechanisms which can produce | | | | 6.5.1 Iluvien 110 |
| first-in-class molecules with more efficiency and | | | | 6.5.2 iCo-007 111 |
| better safety. | | | | 6.6 Profiles of Key Drugs in Macular Degeneration |
| - Develop key strategic initiatives by | | | | Pipeline 111 |
| understanding the key focus areas of the leading | | | | 6.6.1 ACU-4429 111 |
| companies. | | | | 6.6.2 AL-8309 112 |
| - Exploit in-licensing and out-licensing opportunities | | | | 6.7 Profiles of Key Drugs in Allergic Conjunctivitis |
| by identifying products that could fill portfolio gaps. | | | | Pipeline 112 |
| Table of Content | | | | 6.7.1 FOV1101 (Prednisporin) 112 |
| 1 Table of Contents 3 | | | | 7 Global Ophthalmology Therapeutics Market: |
| 1.1 List of Tables 6 | | | | Competitive Landscape 113 |
| 1.2 List of Figures 10 | | | | 7.1 Market Share Analysis: Ophthalmology 113 |
| 2 Global Ophthalmology Therapeutics Market: | | | | 7.2 Competitive Profiling 115 |
| Introduction 13 | | | | 7.2.1 Pfizer 115 |
| 2.1 GBI Research Report Guidance 13 | | | | 7.2.2 Allergan, Inc. 116 |
| 3 Global Ophthalmology Therapeutics Market: | | | | 7.2.3 Alcon, Inc. 118 |
| Market Overview 14 | | | | 7.2.4 Novartis AG 120 |
| 3.1 Introduction 14 | | | | 7.2.5 Merck & Co Inc 122 |
| 3.2 Revenue Forecasts for the Global | | | | 7.2.6 Roche 123 |
| Ophthalmology Therapeutics Market 14 | | | | 8 Global Ophthalmology Therapeutics Market: |
| 3.2.1 Sales Value 14 | | | | Strategic Consolidations 125 |
| 3.2.2 Annual Cost of Therapy 15 | | | | 8.1 Overview 125 |
| 3.2.3 Treatment Usage Patterns 17 | | | | 8.1.1 Valeant Pharmaceuticals International Agrees |
| 3.2.4 Generics' Share in the Global Ophthalmology | | | | to Acquire Aton Pharma Inc 126 |
| Therapeutics Market 23 | | | | 8.1.2 Healthcare of Today, Inc. has Acquired |
| 3.2.5 Sales of Leading Drugs 25 | | | | MacuCLEAR, Inc. 126 |
| 4 Global Ophthalmology Therapeutics Market: | | | | 8.1.3 Opko Health, Inc. has Acquired Pharmacos |
| Therapeutic Landscape 26 | | | | Exakta 126 |
| 4.1 Glaucoma Market 26 | | | | 8.1.4 Sanofi-aventis Acquired Fovea |
| 4.1.1 Introduction 26 | | | | Pharmaceuticals 126 |
| 4.1.2 Unmet Needs 27 | | | | 8.1.5 Alcon, Inc Acquired ESBATech AG 126 |
| 4.1.3 Sales Value 28 | | | | 8.1.6 Aton Pharma, Inc. Acquired Marketing Rights |
| 4.1.4 Sales Volume 29 | | | | to Ophthalmology Drug 126 |
| 4.1.5 Annual Cost of Therapy 30 | | | | 8.2 R&D Licensing Agreements 127 |
| 4.1.6 Treatment Usage Patterns 32 | | | | 8.2.1 General 127 |
| 4.1.7 Geographical Segmentation 39 | | | | 8.2.2 Preclinical and Discovery 127 |
| 4.1.8 Drivers of the Glaucoma Market 41 | | | | 8.2.3 Phase I 128 |
| 4.1.9 Restraints for Glaucoma Market 41 | | | | 8.2.4 Phase II 130 |
| 4.2 Macular Edema 42 | | | | 8.2.5 Phase III 130 |
| 4.2.1 Introduction 42 | | | | 8.2.6 Approved 131 |
| 4.2.2 Unmet Needs 42 | | | | 9 Global Ophthalmology Therapeutics Market: |
| 4.2.3 Sales Value 43 | | | | Appendix 133 |
| 4.2.4 Sales Volume 44 | | | | 9.1 Market Definitions 133 |
| 4.2.5 Annual Cost of Therapy 45 | | | | 9.2 Abbreviations 133 |
| 4.2.6 Treatment Usage Patterns 46 | | | | 9.3 Research Methodology 134 |
| 4.2.7 Geographical Segmentation 52 | | | | 9.3.1 Coverage 134 |
| 4.2.8 Drivers of the Macular Edema Market 54 | | | | 9.3.2 Secondary Research 135 |
| 4.2.9 Restraints For Macular Edema Market 54 | | | | 9.3.3 Primary Research 135 |
| 4.3 Macular Degeneration Market 54 | | | | 9.3.4 Forecasts 135 |
| 4.3.1 Introduction 54 | | | | 9.3.5 Expert Panel Validation 137 |
| 4.3.2 Unmet Needs 55 | | | | 9.4 Contact Us 138 |
| 4.3.3 Sales Value 55 | | | | 9.5 Disclaimer 138 |
| 4.3.4 Sales Volume 56 | | | | 9. |